| 02/09/2021 |
 |
Stage 1 : Estacion de Montana de Manzaneda - A Rua | 118 km | |
| 03/09/2021 | Stage 1 : Estacion Invernal Cabeza de Manzaneda - Estacion Invernal Cabeza de Manzaneda | 7 km | ||
| 04/09/2021 |
|
Stage 2 : Estacion Invernal Cabeza de Manzaneda - Pereiro de Aguiar | 107 km | |
| 05/09/2021 |
 |
Stage 3 : As Pontes - Santiago de Compostela | 107 km |
résultat Stage 3 Madrid Challenge by la Vuelta 2021 (As Pontes - Santiago de Compostela)
| Stage 3: As Pontes-Santiago de Compostela | Total: 107km |
|---|
| 1. | Lotte Kopecky | 2:29:37 |
| 2. | Elisa Longo Borghini | +0:00 |
| 6. | Elisa Balsamo | +0:06 |
| 7. | Katarzyna Niewiadoma | +0:06 |
| 8. | Liane Lippert | +0:08 |
| 9. | Floortje Mackaij | +0:08 |
| 10. | Riejanne Markus | +0:08 |
| 13. | Ellen Van Dijk | +0:08 |
| 16. | Leah Thomas | +0:12 |
| 19. | Evita Muzic | +0:16 |
| Classement | ||
|---|---|---|
| 1. | Annemiek Van Vleuten | 8:40:18 |
| 4. | Coryn Rivera | +1:45 |
| 5. | Liane Lippert | +3:59 |
| 5. | Elisa Balsamo | +1:58 |
| 6. | Katarzyna Niewiadoma | +4:04 |
| 7. | Elisa Longo Borghini | +4:13 |
| 8. | Floortje Mackaij | +4:38 |
| 8. | Alison Jackson | +1:58 |
| 9. | Juliette Labous | +2:38 |
| 10. | Pauliena Rooijakkers | +7:58 |